Unequal cluster sizes in stepped-wedge cluster randomised trials: a systematic review
نویسندگان
چکیده
منابع مشابه
Unequal cluster sizes in stepped-wedge cluster randomised trials: a systematic review
OBJECTIVES To investigate the extent to which cluster sizes vary in stepped-wedge cluster randomised trials (SW-CRT) and whether any variability is accounted for during the sample size calculation and analysis of these trials. SETTING Any, not limited to healthcare settings. PARTICIPANTS Any taking part in an SW-CRT published up to March 2016. PRIMARY AND SECONDARY OUTCOME MEASURES The pr...
متن کاملGroup sequential designs for stepped-wedge cluster randomised trials
BACKGROUND/AIMS The stepped-wedge cluster randomised trial design has received substantial attention in recent years. Although various extensions to the original design have been proposed, no guidance is available on the design of stepped-wedge cluster randomised trials with interim analyses. In an individually randomised trial setting, group sequential methods can provide notable efficiency ga...
متن کاملStepped-wedge cluster randomised trials: where, when and why?
The stepped wedge (SW) cluster randomised trial (CRT) design is being utilised at increasing pace. However, little is known about the standard of reporting of such trials, or how useful the design has proven to be in hindsight. Moreover, much debate exists around when the design should be preferred to the more classical parallel group (PG) CRT. Here, we address these issues by first conducting ...
متن کاملStepped wedge cluster randomised trials: a review of the statistical methodology used and available
BACKGROUND Previous reviews have focussed on the rationale for employing the stepped wedge design (SWD), the areas of research to which the design has been applied and the general characteristics of the design. However these did not focus on the statistical methods nor addressed the appropriateness of sample size methods used.This was a review of the literature of the statistical methodology us...
متن کاملStepped wedge randomised controlled trials: systematic review of studies
Background: In a stepped wedge, cluster randomised trial, clusters receive the intervention at different time points, and the order in which they received it is randomised. Previous systematic reviews of stepped wedge trials have documented a steady rise in their use between 1987 and 2010, which was attributed to the design’s perceived logistical and analytical advantages. However, the interven...
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ژورنال
عنوان ژورنال: BMJ Open
سال: 2017
ISSN: 2044-6055,2044-6055
DOI: 10.1136/bmjopen-2017-017151