Underutilization of Penicillin Skin Testing in the Outpatient Setting

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Recommendations for penicillin skin testing in Taiwan.

Penicillin, or other forms of it, is one of the most commonly prescribed antibiotic used to treat bacterial infections. Penicillin allergy may present with a wide range of symptoms and signs from mild ones such as runny nose, rash or hives on the skin, to deadly angioedema, asthmatic attack, and anaphylactic shock. The purposes of a penicillin skin test (PST) are to identify people at risk of a...

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Utility of minor determinants in penicillin allergy skin testing

Background Penicillin allergy is a major concern among patients and physicians. There’s an estimated 5-10% self reported history of penicillin allergy by patients, but vast majority are not true hypersensitivities. Complete penicillin skin test with both major, minor determinants and amoxicillin is the test of choice for diagnosing IgE-mediated penicillin allergy. While Penicilloyl polylysine (...

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Skin testing only with penicillin G in children with a history of penicillin allergy.

BACKGROUND The absence of commercially available penicilloyl-polylysine (PPL) for most of the last decade severely hampered the practice of penicillin allergy evaluation because skin testing without PPL is reported to have a poor negative predictive value (NPV). OBJECTIVE To determine the safety and NPV of skin testing without PPL using only penicillin G followed by a 3-dose graded challenge ...

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ژورنال

عنوان ژورنال: Journal of Allergy and Clinical Immunology

سال: 2018

ISSN: 0091-6749

DOI: 10.1016/j.jaci.2017.12.114