Understanding Dry Powder Inhalers: Key Technical and Patient Preference Attributes

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[Patient preference in the choice of dry powder inhalers].

OBJECTIVE To investigate a group of patients' preferences among 3 dry powder inhalers--Accuhaler, Easyhaler, and Turbuhaler--and to analyze the features that were most important for motivating choices. MATERIAL AND METHOD The study enrolled 30 patients with stable asthma with a mean (SD) age of 40 (13) and who habitually used inhaled corticosteroids. The patients were shown in detail how to u...

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Assessing dry powder inhalers

To enable what would otherwise be impractical, invasive and potentially dangerous testing, and to remove the huge variation and costs associated with human subjects, it is common practice to test inhalation devices and formulations using in vitro test apparatus. Industry standard test conditions and relevant parameters have been devised and published by the regulatory authorities and within the...

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Dry powder inhalers: an overview.

Dry powder inhalers (DPIs) are a widely accepted inhaled delivery dosage form, particularly in Europe, where they currently are used by a large number of patients for the delivery of medications to treat asthma and chronic obstructive pulmonary disease. The acceptance of DPIs in the United States after the slow uptake following the introduction of the Serevent Diskus in the late 1990s has been ...

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Dry Powder Inhalers: A Review

In the recent years pulmonary drug delivery system is found to be preferred route of administration for various drugs. It has been divided into 3 classes: Nebulizers, pMDI, DPI.DPI are used as an alternative to pMDI because pMDI contains propellant (CFC) which has ozone depletion characteristics. DPI delivers medication in the form of dry powder to lungs. DPI is formulated either as a carrier b...

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Metered-dose inhalers, dry powder inhalers, and transitions.

Since 1956, the pMDI has become the most commonly prescribed and used aerosol device in the world. While concerns about global warming have led to a worldwide ban of CFCs, new HFA-propelled pMDIs are in development, requiring an evolutionary transition in the technology. The phase-out of CFC-propelled pMDIs has stimulated the development of more efficient DPIs, but issues such as cost of device...

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ژورنال

عنوان ژورنال: Advances in Therapy

سال: 2019

ISSN: 0741-238X,1865-8652

DOI: 10.1007/s12325-019-01066-6