Тumor Microenvironment and Obesity

نویسندگان
چکیده

منابع مشابه

Breakfast and Obesity

Breakfast is a main effective component in a safe dietary lifestyle. Obesity is a social and clinical problem of the present century that is highly prevalent among different societies. The worldwide obesity rate has more than doubled since 1980. Many studies showed that the diet of obese people is insufficient. It is also observed that many obese and overweight people skip breakfast or do not p...

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Obesity and Kidney Disease

The rise in the prevalence of chronic kidney disease (CKD) and an increase in the prevalence of obesity in parallel in the recent years is a great concern. CKD increases the rate of cardiovascular disease (CVD) and development of end-stage renal disease, and leads to premature death. Although no direct causality link between obesity and CKD can yet be established, this appears highly probable. ...

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Obesity and Eye Diseases

Background: Obesity is a chronic metabolic disease that has become an epidemic today.  Objective: Although the effects of obesity on the body have been well studied, less is known about obesity and eye health. Methods The present article is a review study. The search was performed using keywords of obesity and eye diseases in PubMed, Scopus, Web of Science databases from 2000 to 2021.  Resul...

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CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment

White adipose tissue (WAT) overgrowth in obesity is linked with increased aggressiveness of certain cancers. Adipose stromal cells (ASCs) can become mobilized from WAT, recruited by tumours and promote cancer progression. Mechanisms underlying ASC trafficking are unclear. Here we demonstrate that chemokines CXCL1 and CXCL8 chemoattract ASC by signalling through their receptors, CXCR1 and CXCR2,...

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High-fat-diet-induced obesity causes an inflammatory and tumor-promoting microenvironment in the rat kidney

Obesity and concomitant comorbidities have emerged as public health problems of the first order. For instance, obese individuals have an increased risk for kidney cancer. However, direct mechanisms linking obesity with kidney cancer remain elusive. We hypothesized that diet-induced obesity (DIO) promotes renal carcinogenesis by inducing an inflammatory and tumor-promoting microenvironment. We c...

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ژورنال

عنوان ژورنال: Acta Scientific Cancer Biology

سال: 2021

ISSN: 2582-4473

DOI: 10.31080/ascb.2021.04.0307