Ultrasound Imaging–Guided Noninvasive Ultrasound Thrombolysis
نویسندگان
چکیده
منابع مشابه
Ultrasound imaging-guided noninvasive ultrasound thrombolysis: preclinical results.
BACKGROUND Catheter-based therapeutic ultrasound thrombolysis was recently shown to be effective and safe. The purpose of this work was to study the safety and efficacy of external high-intensity focused ultrasound thrombolysis guided by ultrasound imaging in experimental settings. METHODS AND RESULTS A therapeutic transducer was constructed from an acoustic lens and integrated with an ultras...
متن کاملThrombolysis by ultrasound.
1. A new method of destroying thrombi in blood vessels by ultrasound and simultaneously removing them is reported. 2. Experiments were performed in twenty dogs with artificial thrombi in the iliac and femoral arteries and veins. The length of the thrombi ranged from 4 to 5 cm and the age from 12 h to 10 days. The unit used consisted of a generator, a frequency counter, an ultrasonic transducer ...
متن کاملNoninvasive, transthoracic, low-frequency ultrasound augments thrombolysis in a canine model of acute myocardial infarction.
BACKGROUND Limitations of coronary thrombolysis include the time to reperfusion, patency rate, and bleeding. We evaluated the use of noninvasive transcutaneous ultrasound to augment coronary thrombolysis. METHODS AND RESULTS In 24 dogs, a thrombotic occlusion of the left anterior descending coronary artery was induced and documented by 12-lead ECG and coronary angiography. After >/=60 minutes...
متن کاملNoninvasive transcutaneous low frequency ultrasound enhances thrombolysis in peripheral and coronary arteries.
Previous studies have shown that external ultrasound with low frequencies and high intensities can enhance thrombolytic drug-induced clot dissolution during in vitro experiments. In this series of studies, we evaluated the efficacy of peripheral and coronary thrombolysis in vivo in animals by using noninvasive transcutaneous ultrasound combined with thrombolytic drugs (streptokinase and tPA) an...
متن کاملUltrasound-enhanced thrombolysis: from bedside to bench.
See related article, pages 1470–1475. Intravenous tissue plasminogen activator (tPA) infusion is the fastest and easiest way to initiate reperfusion therapy in acute stroke. However, poor recovery can still be expected in up to 50% of patients, likely as a result of the initial severity of ischemic insult and slow and incomplete thrombolysis.1,2 Clinical improvement and functional independence ...
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ژورنال
عنوان ژورنال: Circulation
سال: 2000
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.102.2.238