UJI TOKSISITAS AKUT EKSTRAK KUNYIT PUTIH (CURCUMA ZEDOARIA) TERHADAP GAMBARAN HISTOPATOLOGI PANKREAS
نویسندگان
چکیده
Kunyit putih (Curcuma zedoaria) banyak digunakan oleh masyarakat luas karena dipercayai sebagai tanaman herbal yang bermanfaat dalam mengobati bermacam penyakit. Curcumin merupakan salah satu kandungan kunyit diyakini mempunyai manfaat antioxidan, anti inflamasi, mikroba, kanker, aterosklerosis dan diabetes. Secara umum, kepercayaan tehadap penggunaan pengobatan memiliki efek samping minimal jika dibandingkan dengan obat modern, namun penelitian mengenai dari belum diteliti. Tujuan ini adalah agar mengetahui uji toksisitas akut ekstrak terhadap gambaran histopatologi pankreas. Penelitian eksperimental menggunakan design Post Test Only Control Group Design 30 ekor Rattus norvegicus jenis kelamin jantan berat berkisar antara 150-300 gram. Tikus dibagi menjadi kontrol negatif aquades positif NaCMC 1%, 4 kelompok perlakuan dosis 250 mg/KgBB, 500 750 2000 mg/KgBB. Hasil didapat bahwa tidak menunjukkan pada pancreas tikus berupa adanya nekrosis, edema sel radang histologi
منابع مشابه
Analgesic and Antimicrobial Activities of Curcuma Zedoaria
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ژورنال
عنوان ژورنال: Jurnal Kedokteran & Kesehatan
سال: 2022
ISSN: ['2406-7431', '2614-0411']
DOI: https://doi.org/10.32539/jkk.v9i3.19107