UCK2upregulation might serve as an indicator of unfavorable prognosis of hepatocellular carcinoma
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چکیده
منابع مشابه
Reduced Glutamatergic Neurotransmission as Possible Indicator of Unfavorable Prognosis
The paper summarizes the results of experimental and clinical studies showing a reduced function of the glutamatergic neurotransmitter system (GNS) in the development of critical states of the organism. Reduced function of GNS is considered as an unfavorable prognostic factor associated with key mechanisms of thanatogenesis. (Int J Biomed. 2017;7(1):15-23.)
متن کاملthe association of ala133ser polymorphism and methylation in ras association domain family 1a gene with unfavorable prognosis of hepatocellular carcinoma
conclusions the polymorphism and promoter methylation of rassf1a may be a significant factor in hcc, and can be an indicator for poor prognosis in patients with hcc. background the functional and prognostic significance of ras association domain family 1a gene (rassf1a) on hepatocellular carcinoma (hcc) has not been well characterized. objectives this study aimed to investigate the association ...
متن کاملOverexpression of SCAMP3 is an indicator of poor prognosis in hepatocellular carcinoma
SCAMP3, an isoform of the secretory carrier membrane proteins (SCAMPs) family, is a membrane-trafficking protein involved in endosome transport. Previous microarray data showed that SCAMP3 mRNA is highly expressed in hepatocellular carcinoma (HCC). In this study, the expression and clinical significance of SCAMP3 in 100 pairs of HCC and adjacent normal tissue were investigated. siRNA transfecti...
متن کاملElevated expression of UHRF1 predicts unfavorable prognosis for patients with hepatocellular carcinoma.
AIMS The present study was designed to evaluate the different expression of ubiquitin-like with PHD and ring finger domains 1 (UHRF1) in hepatocellular carcinoma (HCC) tissues and the adjacent normal tissues, further explore the correlation between UHRF1 expression and the prognosis of HCC patients. METHODS The UHRF1 expression at protein level in HCC tissues and the adjacent normal tissues w...
متن کاملEvaluation of preoperative elevation of serum c-reactive protein as an indicator for prognosis of colorectal cancer
Abstract Background : Cancer has not been elucidated in colerectal site. C-reactive protein (CRP) is a product synthesized in hepatocytes and has been reported to be up-regulated by such proinflammatory cytokines as interleukin-1 (IL-1), interleukin-6 (IL-6), and tumor necrosis factor (TNF). The significance of a preoperative serum elevation was evaluated using CRP as a predictive i...
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ژورنال
عنوان ژورنال: IUBMB Life
سال: 2018
ISSN: 1521-6543
DOI: 10.1002/iub.1941