Tyrosine Transaminase Induced by Cycloheximide
نویسندگان
چکیده
منابع مشابه
Inhibition of tyrosine transaminase activity by norepinephrine.
The neurotransmitter, norepinephrine, and structurally related primary catecholamines inhibited rat hepatic tyrosine transaminase activity (L-tyrosine:2-oxoglutarate aminotransferase, EC 2.6.1.5) in vitro. The inhibition was competitive with pyridoxal 5’-phosphate cofactor and an “apparent” I& of 4.0 x 10-e M was determined. (The “apparent” K,,, was 6.6 X 10-T M.) Those amines which were associ...
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Since intestinal fluid production in experimental cholera can be limited by cycloheximide, an inhibitor of protein synthesis, the same agent was used to determine whether there are similar mechanisms for fluid production in response to an osmotic gradient. Intestinal fluid production was measured by perfusion of paired rabbit jejunal loops (10 cm) in vivo, in controls, and in animals receiving ...
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Cycloheximide accumulation in a fermentation medium has been shown to be the product of the balance between synthesis and degradation of this antibiotic. Glucose has been shown to prevent cycloheximide degradation. Cycloheximide has been shown to interfere with its own synthesis probably due to feedback inhibition. Approaches for increasing cycloheximide titers in the light of these findings ar...
متن کاملRegulation of tyrosine- -ketoglutarate transaminase in rat liver.
The role of the pancreatic hormones, insulin and glucagon, in the regulation of hepatic tyrosine transaminase (L-tyrosine : Z-oxoglutarate aminotransferase, EC 2.6.1.5) was studied in adrenalectomized rats. Each of these hormones initiated a rapid but limited increase in the enzyme level, which reached a maximum after 2.5 to 3 hours. The optimal doses of insulin and glucagon per 100 g of body w...
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The role of the pancreatic hormones, insulin and glucagon, in the regulation of hepatic tyrosine transaminase (L-tyrosine : Z-oxoglutarate aminotransferase, EC 2.6.1.5) was studied in adrenalectomized rats. Each of these hormones initiated a rapid but limited increase in the enzyme level, which reached a maximum after 2.5 to 3 hours. The optimal doses of insulin and glucagon per 100 g of body w...
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ژورنال
عنوان ژورنال: Science
سال: 1967
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.157.3796.1591-a