Two-Photon Fluorescent Probes for Amyloid-β Plaques Imaging In Vivo
نویسندگان
چکیده
Amyloid-β (Aβ) peptide deposition, hyperphosphorylated tau proteins, reactive astrocytes, high levels of metal ions, and upregulated monoamine oxidases are considered to be the primary pathological markers Alzheimer’s disease (AD). Among them, Aβ deposition or plaques, is regarded as initial factor in pathogenesis AD a critical hallmark AD. This review highlights recently Aβ-specific fluorescent probes for two-photon imaging plaques vivo. It includes synthesis detection mechanism probes, well their application
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ژورنال
عنوان ژورنال: Molecules
سال: 2023
ISSN: ['1420-3049']
DOI: https://doi.org/10.3390/molecules28176184