Two New Dexpanthenol-Containing Wash Gels: Skin Hydration, Barrier Function, and Cosmetic Performance Upon Single and Repeated Usage in Subjects with Dry Skin

Two novel body/face wash gels enriched with emollient ingredients (including dexpanthenol) were developed for the daily care of dry skin. similarly designed 2-week studies (N = 42 each) conducted to assess biophysical and cosmetic performance each new in healthy adults Instrumental measurements quantified effects on stratum corneum (SC) hydration transepidermal water loss (TEWL) (with without a previous sodium lauryl sulfate (SLS) challenge) after single repeated usage. Following applications face gel facial skin, as well SLS-undamaged SLS-damaged skin forearm, significantly increased. Similarly, usage body moisturization increased from baseline; comparisons control areas provided inconsistent results No TEWL observed either product. Both tolerated performances appreciated by subjects. The study suggest that use was associated significant skin-moisturizing adversely affecting barrier function repair.