Two loci affecting B cell responses to B cell maturation factors.
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چکیده
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Two loci affecting B cell responses to B cell maturation factors
B lymphocytes from DBA/2Ha mice have a genetic defect characterized by a failure to differentiate into antibody-secreting cells in response to a family of lymphokines termed B cell maturation factors (BMFs). By contrast, B cells from DBA/2Ha mice respond normally in PFC assays to the B cell mitogen LPS, and macrophages from these mice are activated by one of the three BMFs. Two loci are respons...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1986
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.163.1.116