منابع مشابه
Two-faced TIRs trip the immune switch.
Both Plant and Animal Immune Receptors Can Carry a TIR Domain Mammals, in addition to their adaptive immune system based on somatic evolution of antibodies, carry an innate immune system based on both cell surface and intracellular immune receptors (1). In animals ranging from insects tomammals, Toll-like receptors (TLRs), with extracellular leucine-rich repeats (LRRs) and an intracellular Toll...
متن کاملTwo-Faced Data
Intent One data fragment has several alternative structural representations tailored toward specic data manipulation approaches.
متن کاملThe two-faced T cell epitope
Advances in the field of T cell immunology have contributed to the understanding that cross-reactivity is an intrinsic characteristic of the T cell receptor (TCR), and that each TCR can potentially interact with many different T cell epitopes. To better define the potential for TCR cross-reactivity between epitopes derived from the human genome, the human microbiome, and human pathogens, we dev...
متن کاملTMEM16 chloride channels are two-faced
The Rockefeller University Press $30.00 J. Gen. Physiol. 2016 Vol. 148 No. 5 367–373 https://doi.org/10.1085/jgp.201611686 367 Elucidating the oligomeric structure of ion channels is central to understanding their function (Marsh and Teichmann, 2015). The vast majority of ion channels are formed by multiple subunits organized as an annulus surrounding a solitary, centrally located ion-conductin...
متن کاملTMEM16 chloride channels are two-faced
The Rockefeller University Press $30.00 J. Gen. Physiol. 2016 Vol. 148 No. 5 367–373 https://doi.org/10.1085/jgp.201611686 367 Elucidating the oligomeric structure of ion channels is central to understanding their function (Marsh and Teichmann, 2015). The vast majority of ion channels are formed by multiple subunits organized as an annulus surrounding a solitary, centrally located ion-conductin...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2017
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1700954114