Turning Renewable Feedstocks into a Valuable and Efficient Chiral Phosphate Salt Catalyst

Solketal, the chiral acetonide of glycerol, has been employed as starting material in design a novel punctually phosphate sodium salt for catalytic applications organic and asymmetric synthesis. The racemate two enantiomers substrate are economic commercially available, straightforwardly prepared high yields from naturally occurring feedstocks. Therefore, remarkably, both final catalyst can be synthesized by simple procedures yield compliance with several principles green chemistry. To further demonstrate usefulness catalyst, its application solventless protocol cyanohydrin synthesis series aldehydes presented.