Turning back time

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Turning back the hands of time.

"Mrs Smith, we now have all the information obtainable from your medical history and tests and we find that you are 60-3 years old." "But doctor, there must be a mistake," says the thoroughly startled Mrs Smith, "I am only 50 years old." Mrs Smith, having had a check-up at a clinic using a computerised risk factor appraisal system, now learns that because of her bad habits and life-style she st...

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Turning back time in Markovian process algebra

Product-form solutions in Markovian process algebra (MPA) are constructed using properties of reversed processes. The compositionality of MPAs is directly exploited, allowing a large class of hierarchically constructed systems to be solved for their state probabilities at equilibrium. The paper contains new results on both reversed stationary Markov processes as well as MPA itself and includes ...

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Turning Back Time - What Impact on Performance?

Consistent with the divide-and-conquer approach to problem solving, a recursive result is presented in the domain of stochastic modelling that derives product-form solutions for the steady state probabilities of certain networks composed from interacting Markov chains. Practical applications include multi-tasking operating systems, communication channels and multi-tiered storage systems. The ap...

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Hepatitis C Virus, Inflammation, and Cellular Aging: Turning Back Time.

There is evidence that hepatitis C virus (HCV) infection, like HIV infection, may be associated with chronic inflammation, immune activation, and immune senescence, which contribute to increased risks for cardiometabolic or other diseases outside the liver, as well as to ongoing damage in the liver. These effects may persist after a sustained virologic response (SVR) is achieved with HCV therap...

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Turning back the clock for Schwann cells

Tight junctions loosen up T ight junctions are more flexible than researchers realized, as Shen et al. show. The team discovered that proteins are constantly entering and leaving these connections between epithelial cells. The continual remodeling might allow organisms to adjust the perme-ability of cell layers. In locations such as the skin and the lining of the intestines , epithelial cells s...

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ژورنال

عنوان ژورنال: Nature

سال: 2016

ISSN: 0028-0836,1476-4687

DOI: 10.1038/nature17302