Tunable vegetable oil/silica hybrid microparticles for poorly water-soluble drug delivery
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چکیده
منابع مشابه
Spray freeze-dried porous microparticles of a poorly water-soluble drug for respiratory delivery.
Particles of poorly water-soluble drugs were prepared to develop a dry powder inhaler (DPI). Spray freeze-drying (SFD) technique using a four-fluid nozzle (4N), which has been developed by authors, was applied in this research. Ciclosporin and mannitol were used as a poorly water-soluble model drug and a dissolution-enhanced carrier, respectively. The organic solution of ciclosporin and aqueous...
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Objective(s): Development of an oral sustained-controlled release vehicle which, slowly releases the drug and maintains an effective drug concentration for a long time is aimed.Materials and Methods: A biodegradable magnetic polymeric drug delivery vehicle, using superparamagnetic iron oxide nanoparticles encapsulating by polyvinylpyrrolidone-block-polyethylene glycol-block-poly methacrylic aci...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2019
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2019.118478