Tumors of the Soft Tissues

Soft tissues

The deposition of amorphous calcium salts within the soft tissues is variously called mineralization or calcification. Two forms of calcium salts may be found in the soft tissues: calcium pyrophosphate dihydrate and calcium hydroxyapatite. If bony trabeculae are discernible within the mineralized focus the term ossification is used, sometimes prefixed with the terms ectopic or heterotopic. Ther...

Genetic and molecular abnormalities in tumors of the bone and soft tissues.

BACKGROUND Malignant transformation requires the accumulation of multiple genetic alterations such as chromosomal abnormalities, oncogene activation, loss of tumor suppressor genes, or abnormalities in genes that control DNA repair and genomic instability. Sarcomas are a heterogeneous group of malignant mesenchymal tumors of difficult histologic classification and strong genetic predisposition....

Surgical Treatment of the Soft Tissues

Wounds and Injuries of the Soft Tissues

To maximize the preservation of life and minimize the attendant morbidity of battle wounds, the surgeon attempts to localize or isolate the deleterious effects of injury and to optimize healing. This objective is best accomplished by removal of all foreign material and detached or severely disrupted muscle from the wound, by the establishment of open drainage of the wound’s recesses, and by mai...

The fracture toughness of soft tissues.

Fracture toughness is important for any material, but to date there have been few investigations of this mechanical property in soft mammalian tissues. This paper presents new data on porcine muscle tissue and a detailed analysis of all previous work. The conclusion is that, in most cases, fracture toughness has not in fact been measured for these tissues. Reanalysis of the previous work shows ...