Tumor Rejection by Disturbing Tumor Stroma Cell Interactions
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چکیده
منابع مشابه
Tumor Rejection by Disturbing Tumor Stroma Cell Interactions
The stroma of solid tumors is a complex network of different cell types. We analyzed stroma cell interactions in two tumor models during cyclophosphamide (Cy)-induced tumor rejection. In growing tumors, tumor infiltrating macrophages (TIMs) produced interleukin (IL)-10. Beginning 6 h after Cy-treatment T cells in the tumor were inactivated and TIMs switched to interferon (IFN)-gamma production....
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2001
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.194.11.1549