Tumor necrosis factor α Inhibition for Alzheimer’s Disease
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چکیده
منابع مشابه
Tumor necrosis factor α Inhibition for Alzheimer’s Disease
Tumor necrosis factor α (TNF-α) plays a central role in the pathophysiology of Alzheimer's disease (AD). Food and Drug Administration-approved biologic TNF-α inhibitors are thus a potential treatment for AD, but they do not cross the blood-brain barrier. In this short review, we discuss the involvement of TNF-α in AD, challenges associated with the development of existing biologic TNF-α inhibit...
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ژورنال
عنوان ژورنال: Journal of Central Nervous System Disease
سال: 2017
ISSN: 1179-5735,1179-5735
DOI: 10.1177/1179573517709278