Tumor eradication in rat glioma and bypass of immunosuppressive barriers using internal radiation with 188Re-lipid nanocapsules
نویسندگان
چکیده
منابع مشابه
Tumor eradication in rat glioma and bypass of immunosuppressive barriers using internal radiation with (188)Re-lipid nanocapsules.
To date, glioblastoma treatments have only been palliative. In this context, locoregional drug delivery strategies, which allow for blood--brain barrier bypass and reduced systemic toxicity, are of major significance. Recent progress in nanotechnology has led to the development of colloidal carriers of radiopharmaceutics, such as lipid nanocapsules loaded with rhenium-188 (LNC(188)Re-SSS) that ...
متن کاملTumor Eradication in Rat Glioma and Bypass of Immunosuppressive Barriers Using Internal Radiation With
To date, glioblastoma treatments have only been palliative. In this context, locoregional drug delivery strategies, which allow for blood-brain barrier bypass and reduced systemic toxicity, are of major significance. Recent progress in nanotechnology has led to the development of colloidal carriers of radiopharmaceutics, such as lipid nanocapsules loaded with rhenium-188 (LNC 188 Re-SSS) that a...
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BACKGROUND Due to their nanometric scale (50 nm) along with their biomimetic properties, lipid nanocapsules loaded with Rhenium-188 (LNC(188)Re-SSS) constitute a promising radiopharmaceutical carrier for hepatocellular carcinoma treatment as its size may improve tumor penetration in comparison with microspheres devices. This study was conducted to confirm the feasibility and to assess the effic...
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ژورنال
عنوان ژورنال: Biomaterials
سال: 2011
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2011.05.067