منابع مشابه
Tumor budding in colorectal carcinomas.
OBJECTIVE In colorectal carcinomas, tumor budding has been defined as the presence of isolated single tumor cells or small cell clusters in the stroma at the invasive tumor margin. In this study, the relationship between tumor budding density at the invasive tumor margin and pathological parameters is investigated. MATERIAL AND METHOD Haematoxylin and eosin stained slides of 73 cases with col...
متن کاملTumor Budding in Upper Gastrointestinal Carcinomas
The basis of personalized medicine in oncology is the prediction of an individual's risk of relapse and death from disease. The presence of tumor budding (TB) at the tumor-host interface of gastrointestinal cancers has been recognized as a hallmark of unfavorable disease biology. TB is defined as the presence of dedifferentiated cells or small clusters of up to five cells at the tumor invasive ...
متن کاملEpithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: Tumor budding as oncotarget
Epithelial mesenchymal transition (EMT) is proposed as a critical mechanism for the acquisition of malignant phenotypes by epithelial cells. In colorectal cancer, tumor cells having undergone EMT are histologically represented by the presence of tumor buds defined as single cells or small clusters of de-differentiated tumor cells at the invasive front. Tumor budding is not a static, histologica...
متن کاملCirculating cytokeratin-positive cells and tumor budding in colorectal cancer
AIM To investigate whether circulating cytokeratin-positive (CK+) cells in the mesenteric blood of resected colorectal specimens are prognostic and correlate with tumor budding. METHODS Fifty-six colorectal specimens were collected between 9/2007 and 7/2008. Blood from the mesenteric vein was drawn immediately after receiving the fresh and unfixed specimens in the pathology department. After ...
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ژورنال
عنوان ژورنال: Turkish Journal of Pathology
سال: 2012
ISSN: 1018-5615,1309-5730
DOI: 10.5146/tjpath.2012.01099