Tubulointerstitial nephritis with anti-neutrophil cytoplasmic antibody following indomethacin treatment

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Tubulointerstitial nephritis with anti-neutrophil cytoplasmic antibody following indomethacin treatment.

Sir, Tubulointerstitial diseases including tubulointerstitial nephritis (TIN) have an impact on overall renal function and eventual prognosis of renal diseases [1]. However, the detailed pathogenesis of human TIN has not been fully studied. Renal involvement in anti-neutrophil cytoplasmic antibody (ANCA)-associated diseases shows mainly glomerular lesion, especially necrotizing crescentic glome...

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Concurrent IgG4-related tubulointerstitial nephritis and IgG4 myeloperoxidase-anti-neutrophil cytoplasmic antibody positive crescentic glomerulonephritis

RATIONALE IgG4-related disease (IgG4-RD) is a newly recognized systemic disease. The typical pathological finding in the kidney is abundant IgG4-positive plasma cell infiltration with characteristic storiform fibrosis in the interstitium. Antibodies of the IgG4 subclass have been linked to certain autoimmune diseases including antiproteinase 3 (PR3) anti-neutrophil cytoplasmic antibody (ANCA) o...

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Acute tubulo-interstitial nephritis with positive anti-neutrophil cytoplasmic antibodies.

INTRODUCTION Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis involving the kidney usually comprises pauci-immune, necrotizing glomerulonephritis with crescents. Mononuclear tubulo-interstitial infiltrates are common in ANCA associated vasculitis, but these have usually been described in conjunction with glomerulitis. Acute tubulo-interstitial nephritis (ATIN) is a common cause...

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[Treatment of anti-neutrophil cytoplasmic antibody related vasculitis].

ANCA-associated vasculitides are a well-known clinico-pathological group of systemic diseases comprising microscopic poliangiitis, granulomatosis with poliangiitis and eosinophilic granulomatosis with poliangiitis. This article shows contemporary treatment of this diseases with extensive literature review. Stepwise treatment of ANCA-associated vasculitides is divided into induction therapy and ...

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Treatment and clinicopathological characteristics of lupus nephritis with anti-neutrophil cytoplasmic antibody positivity: a case–control study

OBJECTIVE To assess the clinical features, pathological presentations, treatments and outcomes of lupus nephritis (LN) with anti-neutrophil cytoplasmic antibody (ANCA) positivity. DESIGN A case-control study. METHODS Patients (n=49) were retrospectively included from Jinling Hospital in China if presenting with biopsy-proven ANCA-positive LN between 1985 and 2008. Clinicopathological charac...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 1999

ISSN: 1460-2385,0931-0509

DOI: 10.1093/ndt/14.11.2774