Tubulo-interstitial nephritis with Fanconi syndrome in Behcet disease

Tubulo-interstitial nephritis with Fanconi syndrome in Behçet disease.

Behçet disease (BD) is a chronic and inflammatory systemic disorder of unknown aetiology, with an estimated prevalence of 1/500 000 in Europe and the United States. BD, which typically affects young adult males, is characterized by recurrent oral and genital ulcerations, with anterior or posterior uveitis. Skin, joint, nervous system, lung and gastrointestinal tract manifestations are common, a...

Acute tubulo-interstitial nephritis with positive anti-neutrophil cytoplasmic antibodies.

INTRODUCTION Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis involving the kidney usually comprises pauci-immune, necrotizing glomerulonephritis with crescents. Mononuclear tubulo-interstitial infiltrates are common in ANCA associated vasculitis, but these have usually been described in conjunction with glomerulitis. Acute tubulo-interstitial nephritis (ATIN) is a common cause...

Keep an eye out for tubulo-interstitial nephritis.

Acute tubulo-interstitial nephritis and uveitis syndrome (TINU) is a rare disease, generally presenting in young women. We describe a 16-year-old Turkish girl with aspecific symptoms and elevated serum creatinine. Further, she complained about a burning pain in her left eye. Renal biopsy revealed acute TIN. Other conditions were excluded and TINU was diagnosed.

Immunologically mediated chronic tubulo-interstitial nephritis caused by valproate therapy.

Pathophysiology of Chronic Tubulo - Interstitial Disease in Rats

The human end-stage kidney and its experimental analogue, the remnant kidney in the rat, exhibit widespread tubulointerstitial disease. We investigated whether the pathogenesis of such tubulo-interstitial injury is dependent upon adaptive changes in tubular function and, in particular, in ammonia production when renal mass is reduced. Dietary acid load was reduced in 143nephrectomized rats by d...