منابع مشابه
TSH screening
That means there is considerable overlap in what we would consider the true euthyroid state in a patient. Hence, a population may be well characterised by this screening process, but it doesn't closely reflect the individual situation. As a result, an abnormal result of the population-based screening should not necessarily translate into an automatic decision on the requirement of treatment. Th...
متن کاملFolding-dependent binding of thyrotropin (TSH) and TSH receptor autoantibodies to the murine TSH receptor ectodomain.
The mouse TSH receptor ectodomain (mTSHR-ecd) was amplified from murine thyroid complementary DNA and ligated into the pAcGP67B insect cell vector, and the nucleotide sequence was confirmed. Employing a baculovirus-insect cell system, the mTSHR-ecd (amino acids 22-415) was expressed as a fusion protein with the gp67 insect cell signal sequence at the NH2-terminus and a C-terminal six-histidine ...
متن کاملTSH-CHECK-1 Test: Diagnostic Accuracy and Potential Application to Initiating Treatment for Hypothyroidism in Patients on Anti-Tuberculosis Drugs
BACKGROUND Thyroid-stimulating hormone (TSH) promotes expression of thyroid hormones which are essential for metabolism, growth, and development. Second-line drugs to treat tuberculosis (TB) can cause hypothyroidism by suppressing thyroid hormone synthesis. Therefore, TSH levels are routinely measured in TB patients receiving second-line drugs, and thyroxin treatment is initiated where indicate...
متن کاملHow to Check Urinary Incontinence
دیواره مثانه شامل شبکه انبوهی از فیبرهای عضلانی صاف می باشد که از افزایش ناگهانی فشار مثانه که منجر به انقباض و نشت ادرار از مثانه قبل از پرشدن کامل آن می شود جلوگیری می کند و حدود ۵۰۰ سی سی ادرار را در خود جای می دهد. مجرای پیشابراه که بعنوان محل خروجی برای مثانه محسوب می شود شامل دو لایه عضله صاف و یک ناحیه تنگ شده عضلانی است که تحت کنترل ارادی می باشد و بعنوان اسفنکتر خارجی عمل می کند. هنگام...
متن کاملTSH signalling and cancer.
Thyroid cancers are the most frequent endocrine neoplasms and mutations in the thyrotropin receptor (TSHR) are unusually frequent. Here we present the state-of-the-art concerning the role of TSHR in thyroid cancer and discuss it in light of the cancer stem cell theory or the classical view. We briefly review the gene and protein structure updating the cancer related TSHR mutations database. Int...
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ژورنال
عنوان ژورنال: CME
سال: 2015
ISSN: 1614-371X,1614-3744
DOI: 10.1007/s11298-015-1411-9