Tryptophan-Assisted Synthesis Reduces Bimetallic Gold/Silver Nanoparticle Cytotoxicity and Improves Biological Activity
نویسندگان
چکیده
منابع مشابه
Nanoparticle Incorporation of Melittin Reduces Sperm and Vaginal Epithelium Cytotoxicity
Melittin is a cytolytic peptide component of bee venom which rapidly integrates into lipid bilayers and forms pores resulting in osmotic lysis. While the therapeutic utility of free melittin is limited by its cytotoxicity, incorporation of melittin into the lipid shell of a perfluorocarbon nanoparticle has been shown to reduce its toxicity in vivo. Our group has previously demonstrated that per...
متن کاملMicrowave Assisted Synthesis and Biological Activity of Novel Coumarinyltriazolothiadiazoles
A series of new 3-(4-methylcoumarinyl-7-oxymethyl)-6-substitutedphenyl-5,6-dihydro-s-triazolo (3,4-b)(1,3,4)-thiadiazoles 2(a-j) have been synthesized by reacting 5-(4-methyl coumarinyl-7-oxymethyl)-4-amino-3-mercapto(4H)-1,2,4-triazole with various aromatic aldehydes by microwave assisted organic synthesis. The structure of the compounds 2 (a-j) has been confirmed by IR, (1)H NMR and mass spec...
متن کاملSynthesis, Characterization, and Biological Activity Studies on Fanlizhicyclopeptide A
The synthesis of a proline-rich cyclic heptapeptide, fanlizhicyclopeptide A (8), previouslyisolated from the fruits of Annona squamosa (sugar-apples), is described via coupling oftetrapeptide l-prolyl-l-tyrosyl-l-leucyl-l-proline methyl ester with tripeptide Boc-glycyl-lvalyl-l-proline followed by cyclization of the linear fragment having seven amino acid units.Structure of the synthesized cycl...
متن کاملSynthesis, Characterization, and Biological Activity Studies on Fanlizhicyclopeptide A
The synthesis of a proline-rich cyclic heptapeptide, fanlizhicyclopeptide A (8), previouslyisolated from the fruits of Annona squamosa (sugar-apples), is described via coupling oftetrapeptide l-prolyl-l-tyrosyl-l-leucyl-l-proline methyl ester with tripeptide Boc-glycyl-lvalyl-l-proline followed by cyclization of the linear fragment having seven amino acid units.Structure of the synthesized cycl...
متن کاملUranyle Complexes: synthesis, evaluation of biological activity
In this research, some of the inorganic complexes of uranyl with N- donor ligandswere synthesized. Complexes were characteriezed by FT-IR and UV spectra, ¹HNMR,¹³CNMR and some physical properties. The uranyl unit (UO2) is composed of a center ofuranium atom with the charge (+6) and two oxygen atom by forming two U=O double bonds.The structure is linear (O=U=O, 180) and usually stable. So other ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nanobiomedicine
سال: 2014
ISSN: 1849-5435,1849-5435
DOI: 10.5772/59684