TRPV1 is a novel target for omega-3 polyunsaturated fatty acids
نویسندگان
چکیده
منابع مشابه
TRPV1 is a novel target for omega-3 polyunsaturated fatty acids.
Omega-3 (n-3) fatty acids are essential for proper neuronal function, and they possess prominent analgesic properties, yet their underlying signalling mechanisms are unclear. Here we show that n-3 fatty acids interact directly with TRPV1, an ion channel expressed in nociceptive neurones and brain. These fatty acids activate TRPV1 in a phosphorylation-dependent manner, enhance responses to extra...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2007
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2006.121988