Trough to peak ratio: current status and applicability

Peak and Trough.

Reproducibility and Clinical Value of the Trough-to-Peak Ratio of the Antihypertensive Effect

The objectives of our study were to assess the reproducibility of the trough-to-peak ratio (T/P) and to see whether a high T/P is accompanied by more organ protection or vice versa. The study included 175 (mean6SD age, 5169 years) subjects with mild-moderate essential hypertension who had echocardiographic evidence of left ventricular (LV) hypertrophy taken from the SAMPLE study (Study on Ambul...

Dclcri~liiliilg lllc Trough-to-Peak Ratio in Parallel-Group Trials

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Dow Theory’s Peak-and-Trough Analysis Justified

In the analysis of dynamic financial quantities such as stock prices, equity prices, etc., reasonable results are often obtained if we only consider local maxima (“peaks”) and local minima (“troughs”) and ignore all the other values. The empirical success of this strategy remains a mystery. In this paper, we provide a possible explanation for this success. 1 Formulation of the Problem Peak-and-...

Reproducibility and clinical value of the trough-to-peak ratio of the antihypertensive effect: evidence from the sample study.

The objectives of our study were to assess the reproducibility of the trough-to-peak ratio (T/P) and to see whether a high T/P is accompanied by more organ protection or vice versa. The study included 175 (mean+/-SD age, 51+/-9 years) subjects with mild-moderate essential hypertension who had echocardiographic evidence of left ventricular (LV) hypertrophy taken from the SAMPLE study (Study on A...