Triterpenic Acids and Flavonoids from Satureja parvifolia. Evaluation of their Antiprotozoal Activity

Triterpenic acids and flavonoids from Satureja parvifolia. Evaluation of their antiprotozoal activity.

Bioassay-guided fractionation of a Satureja parvifolia MeOH extract led to the isolation of eriodictyol, luteolin and ursolic and oleanolic acids as its active components against Plasmodium falciparum K1. This is the first time these compounds are reported as constituents of S. parvifolia. Ursolic acid showed an IC50 of 4.9 microg/ml, luteolin 6.4 microg/ml, oleanolic acid 9.3 microg/ml and eri...

Antiprotozoal activity of flavonoids from Eupatorium arnottianum

María Clavin1, Silvia Cazorla2,3, Renata Spina4, Miguel A. Sosa4, Emilio Malchiodi2, Virginia Martino1, Fernanda Frank2,3,†, Liliana Muschietti1,†,* 1Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Cátedra de Farmacognosia. IQUIMEFA (UBACONICET), Junín 956 2° F (1113), Buenos Aires, Argentina. 2Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Cátedra de Inmunologí...

Bioactive flavonoids from Satureja atropatana Bonge.

From the ethyl acetate and methanol extract of the aerial parts of Satureja atropatana Bonge, which belongs to the Lamiaceae family, four flavonoids were isolated. Their structures were determined to be 5,6,3'-trihydroxy-7,8,4'-trimethoxyflavone (1), 5,6-dihydroxy-7,8,3',4'-tetramethoxyflavone or 5-desmethoxynobiletin (2), 5,6,4'-trihydroxy-7,8,3'-trimethoxyflavone or thymonin (3) and luteolin ...

detection of volatile compounds of medicinal plants with some nano-sorbents using modified or new methodologies and investigation of antioxidant activity of their methanolic extracts

in this work, a novel and fast method for direct analysis of volatile compounds (davc) of medicinal plants has been developed by holding a filament from different parts of a plant in the gc injection port. the extraction and analysis of volatile components of a small amount of plant were carried out in one-step without any sample preparation. after optimization of temperature, extraction time a...

Flavonoids from Cleistocalyx operculatus Buds and their Cytotoxic Activity