Triplex target sites of MEG3 RNA-chromatin interactions
نویسندگان
چکیده
منابع مشابه
Triplex target sites of MEG3 RNA-chromatin interactions [version 1; referees: awaiting peer review]
Many long noncoding RNAs are bound to chromatin. MEG3 binds to multiple different genomic locations, containing GA-rich motifs, and form RNA-DNA triplex structures. In this work, we test whether the MEG3 binding sites are specific enough to be regulated by a particular lncRNA. We show that at least in the case of MEG3, a subset of the triplex target sites (TTS) is able to hybridize with various...
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Many long noncoding RNAs are bound to chromatin. MEG3 binds to multiple different genomic locations, containing GA-rich motifs, and form RNA-DNA triplex structures. In this work, we test whether the MEG3 binding sites are specific enough to be regulated by a particular lncRNA. We show that at least in the case of MEG3, a subset of the triplex target sites (TTS) is able to hybridize with various...
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ژورنال
عنوان ژورنال: F1000Research
سال: 2018
ISSN: 2046-1402
DOI: 10.12688/f1000research.13522.1