Triplet stabilization for enhanced drug photorelease from sunscreen-based photocages
نویسندگان
چکیده
The importance of the relative triplet excited state energies avobenzone (our phenacyl-like photolabile group) and ketoprofen photocaged drug) has been demonstrated by means spectroscopic experiments theoretical calculations.
منابع مشابه
Sunscreen-Based Photocages for Topical Drugs: A Photophysical and Photochemical Study of A Diclofenac-Avobenzone Dyad.
Photosensitization by drugs is a problem of increasing importance in modern life. This phenomenon occurs when a chemical substance in the skin is exposed to sunlight. Photosensitizing drugs are reported to cause severe skin dermatitis, and indeed, it is generally advised to avoid sunbathing and to apply sunscreen. In this context, the nonsteroidal anti-inflammatory drug (NSAID) diclofenac is a ...
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ژورنال
عنوان ژورنال: Organic and Biomolecular Chemistry
سال: 2021
ISSN: ['1477-0520', '1477-0539']
DOI: https://doi.org/10.1039/d0ob02244f