Tricyclic antidepressant overdose necessitating ICU admission
نویسندگان
چکیده
منابع مشابه
Tricyclic antidepressant overdose necessitating ICU admission.
Tricyclic antidepressant (TCA) overdose necessitating intensive care unit (ICU) admission remains a significant problem in the Western Cape. In this retrospective study, we reviewed the course of life-threatening TCA overdose in our centre to identify potential prognostic indicators. TCA levels >1000 ng/ml were associated with QT and QRS prolongation and convulsions. However, no single paramete...
متن کاملTricyclic antidepressant overdose: a review.
Overdoses of tricyclic antidepressants are among the commonest causes of drug poisoning seen in accident and emergency departments. This review discusses the pharmacokinetics, clinical presentation and treatment of tricyclic overdose.
متن کاملRisk assessment of severe tricyclic antidepressant overdose.
Prognostic factors for severe complications in tricyclic antidepressant (TCA) overdose remain unclear. We therefore evaluated the value of clinical characteristics and electrocardiograph (ECG) parameters to predict serious events (seizures, arrhythmia, death) in severe TCA overdose of 100 patients using logistic regression models for risk assessment. The overall fatality rate was 6%, arrhythmia...
متن کاملComplicated infective endocarditis necessitating ICU admission: clinical course and prognosis
AIM To study incidence, clinical course and prognostic factors in patients admitted to medical intensive care units (ICUs) because of a complicated course of infective endocarditis. METHOD This was a retrospective multicenter observational study of 4106 patients admitted to four medical ICUs in one tertiary hospital and one university hospital between 1994 and 1999. RESULTS Infective endoca...
متن کاملCriteria for admitting patients with tricyclic antidepressant overdose.
Several investigators have recently developed guidelines for determining which patients with tricyclic antidepressant overdose should be hospitalized. The width of the QRS complex on the ECG and several clinical parameters have been proposed to identify patients at risk for major complications. To validate these, we developed an algorithm and then applied it to 45 patients who had overdosed on ...
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ژورنال
عنوان ژورنال: South African Medical Journal
سال: 2012
ISSN: 2078-5135
DOI: 10.7196/samj.5300