Trends in Regenerative Medicine: Repigmentation in Vitiligo Through Melanocyte Stem Cell Mobilization
نویسندگان
چکیده
منابع مشابه
Vitiligo Repigmentation: What’s New?
Vitiligo is a relatively common acquired skin disorder, characterized by the progressive loss of melanocytes, which results in white patches. Classically, vitiligo’s treatments have been considered unsatisfactory and challenging. Recent advances in the knowledge of vitiligo’s pathogenesis have contributed to find better therapeutic options, so that at present many patients find a solution for d...
متن کاملStem cell and regenerative medicine.
Stem cells have been identified and isolated in many adult tissues. They exhibit a great plasticity and the ability to give rise to differentiated cells of several lineages. The possibility of transplantation of these stem cells into an adult to develop, integrate and rebuild destroyed tissues or organs has encouraged the study of the mechanisms of the differentiation of stem cells. These cells...
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Background: In many years, finding modern and appropriate treatments for diseases, especially chronic diseases (such as chronic metabolic diseases) have been one of the most important issues. On the other hand, limitations related to organ transplantation have made a serious need for advanced therapeutic strategies. In this respect, researchers have recognized the benefits of stem cells as a su...
متن کاملUpdate on skin repigmentation therapies in vitiligo.
Treatment for vitiligo is difficult and prolonged. Nevertheless, at present considerable knowledge accumulated during several decades on the pathogenic mechanisms, revealed important clues for designing new strategies to improve vitiligo depigmentation. With available medical therapies, high repigmentation percentages mostly on facial and neck lesions are achieved, although they are less effect...
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Hematopoietic stem/progenitor cells (HSPCs) which give rise to different blood cell types are present within the bone marrow microenvironment, especially in flat bones such as skull, vertebrae, pelvis and chest. Interacting factors such as stromal derived factor-1/CXCR4, very late antigen-4/vascular cell adhesion molecule-1, Lymphocyte function-associated antigen-1/ intercellular adhesion molec...
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ژورنال
عنوان ژورنال: Medicinal Research Reviews
سال: 2016
ISSN: 0198-6325
DOI: 10.1002/med.21426