Treatment with Growth Hormone for Adults with Growth Hormone Deficiency Syndrome: Benefits and Risks
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چکیده
منابع مشابه
Treatment with Growth Hormone for Adults with Growth Hormone Deficiency Syndrome: Benefits and Risks
Pharmacological treatment of growth hormone deficiency (GHD) in adults began in clinical practice more than 20 years ago. Since then, a great volume of experience has been accumulated on its effects on the symptoms and biochemical alterations that characterize this hormonal deficiency. The effects on body composition, muscle mass and strength, exercise capacity, glucose and lipid profile, bone ...
متن کاملQuality of life assessment before and after growth hormone treatment in adults with growth hormone deficiency.
The effect of recombinant human growth hormone (rhGH) treatment on the quality of life was studied in adults with growth hormone deficiency (GHD). Twenty-four adults who satisfied strict criteria for GHD took part in a double-blind, placebo-controlled, 6-month trial. 'Quality of life' assessment was performed at entry into the trial and after 1 month and 6 months, by means of self-rating questi...
متن کاملAdult Growth Hormone Deficiency – Benefits, Side Effects, and Risks of Growth Hormone Replacement
Deficiency of growth hormone (GH) in adults results in a syndrome characterized by decreased muscle mass and exercise capacity, increased visceral fat, impaired quality of life, unfavorable alterations in lipid profile and markers of cardiovascular risk, decrease in bone mass and integrity, and increased mortality. When dosed appropriately, GH replacement therapy (GHRT) is well tolerated, with ...
متن کاملTreatment of growth hormone deficiency in adults.
BACKGROUND The Growth Hormone Research Society held a Consensus Workshop in Sydney, Australia, in March 2007 to review advances in the management of growth hormone (GH) deficiency in adults and to update consensus recommendations. OBJECTIVE This short review summarizes key background information presented at the workshop and the consensus recommendations that followed. CONCLUSIONS The benef...
متن کاملPoland's syndrome associated with growth hormone deficiency.
A 9 year old boy with Poland's syndrome (absence of the left pectoralis major muscle associated with an ipsilateral malformation of the hand) and isolated growth hormone deficiency, owing to anatomical abnormalities of the pituitary gland, is described. MRI brain scan showed severe hypoplasia of both the sella and anterior lobe of the pituitary gland with absence of the pituitary stalk and ecto...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2018
ISSN: 1422-0067
DOI: 10.3390/ijms19030893