Treatment response of CNS high‐grade neuroepithelial tumors with MN1 alteration

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چکیده

منابع مشابه

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Primitive neuroectodermal tumors of the central nervous system (CNS-PNETs) are highly aggressive, poorly differentiated embryonal tumors occurring predominantly in young children but also affecting adolescents and adults. Herein, we demonstrate that a significant proportion of institutionally diagnosed CNS-PNETs display molecular profiles indistinguishable from those of various other well-defin...

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Dysembryoplastic Neuroepithelial Tumors.

Dysembryoplastic neuroepithelial tumor (DNT) is a benign glioneuronal neoplasm that most commonly occurs in children and young adults and may present with medically intractable, chronic seizures. Radiologically, this tumor is characterized by a cortical topography and lack of mass effect or perilesional edema. Partial complex seizures are the most common presentation. Three histologic subtypes ...

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Dysembryoplastic neuroepithelial tumors: MR appearance.

PURPOSE Dysembryoplastic neuroepithelial tumor (DNT) is a newly described, pathologically benign tumor arising within the supratentorial cortex and having a 100% association with partial complex seizures. We reviewed the MR appearance of the brains of six patients with DNT, without and with administration of gadolinium-DTPA, emphasizing the clinical and radiologic features. METHODS The MR ima...

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Malignant Transformation Potential of Dysembryoplastic Neuroepithelial Tumors

Dysembryoplastic neuroepithelial tumor is a relatively recently recognized neuropathological entity that was first proposed in 1988. It is typically considered either a quasi-hamartomatous lesion or a benign, low-grade mixed glioneuronal tumor, and is of World Health Organization grade I classification. Earlier studies suggested the clinical stability of this entity given the predominant lack o...

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ژورنال

عنوان ژورنال: Pediatric Blood & Cancer

سال: 2020

ISSN: 1545-5009,1545-5017

DOI: 10.1002/pbc.28627