Treatment of chronic pain: antidepressant, antiepileptic and antiarrhythmic drugs
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چکیده
منابع مشابه
Treatment of Neuropathic Pain: Antiepileptic and Antidepressant Drugs - Printer-friendly version
Neuropathic Pain Neuropathic pain was originally defi ned by the International Association for the Study of Pain (IASP), in 1994, as “pain initiated or caused by a primary lesion or dysfunction in the nervous system” [57]. In 2008, Treede et al. proposed a redefi nition to “pain arising as a direct consequence of a lesion or disease aff ecting the somatosensory system” [78]. Since then, the IAS...
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The development of newer classes of antidepressants and second-generation antiepileptic drugs has created unprecedented opportunities for the treatment of chronic pain. These drugs modulate pain transmission by interacting with specific neurotransmitters and ion channels. The actions of antidepressants and antiepileptic drugs differ in neuropathic and non-neuropathic pain, and agents within eac...
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Antiepileptic drugs (AEDs) are extensively used worldwide to treat a wide range of disorders other than epilepsy, such as neuropathic pain, migraine, and bipolar disorder. Due to this situation more than 20 new third-generation AEDs have been introduced in the market recently. The future design of new AEDs must also have potential to help in the non-epileptic disorders. The wide acceptance of s...
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Most patients with cardiac arrhythmias require treatment with antiarrhythmic drugs, although recent advances in surgical and electrical techniques are promising. The ideal antiarrhythmic compound should have: (1) A wide range of therapeutic activity in both atrial and ventricular arrhythmias. (2) Parenteral and oral formulations to permit simple dosage schedules. (3) Pharmacokinetic properties ...
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ژورنال
عنوان ژورنال: Continuing Education in Anaesthesia Critical Care & Pain
سال: 2005
ISSN: 1743-1816
DOI: 10.1093/bjaceaccp/mki003