Treatment of Anxiety States by Antidepressant Drugs

Treatment of childhood depression with antidepressant drugs.

Mouse Models for Studying Depression-Like States and Antidepressant Drugs.

Depression is a common psychiatric disorder, with diverse symptoms and high comorbidity with other brain dysfunctions. Due to this complexity, little is known about the neural and genetic mechanisms involved in depression pathogenesis. In a large proportion of patients, current antidepressant treatments are often ineffective and/or have undesirable side effects, fueling the search for more effe...

Antidepressant Drugs

Depression is a common mental disorder characterized by sadness, loss of interest or pleasure, feelings of guilt or low self-esteem, sleep or appetite disturbances, fatigue and lack of concentration. The disorder can be either chronic or recurrent, substantially reducing the individual’s capacity to work or study, or perform the activities of daily living [1]. Depression is more common in women...

Anti-Inflammatory Activity of a Selection of Antidepressant Drugs

      Anti-inflammatory activity has been reported for a few of antidepressant drugs and in contrary sertraline has potentiated inflammation. In this study, anti-inflammatory effect of a collection of antidepressant drugs belonging to different classes was evaluated to help a rational selection of these drugs in disease conditions such as association of depression or anxiety with inflammatory d...

Antidepressant drugs in the treatment of obsessive-compulsive disorders.

Most reports of drug treatment for obsessivecompulsive neurosis concern one tricyclic antidepressant, namely clomipramine. Early suggestions that the drug might be valuable in this condition were based on uncontrolled and/or short-term studies over only a few weeks (Fernandez and Lopez-Ibor, 1967; Beaumont, 1973; Capstick, 1975; Ananth et al., 1978). A recent controlled study with long-term fol...