Treatment of Anticholinesterase Poisoning

The manifestations and treatment of poisoning due to nerve gas and other organic phosphate anticholinesterase compounds.

Pathophysiological and clinical aspects of combat anticholinesterase poisoning.

Nerve agents are organophosphate compounds similar to those used as pesticides but with much higher toxicity. They all block the activity of the enzyme acetylcholine esterase. Victims are intoxicated by absorption of the toxin via exposed skin or, more commonly, via inhalation of the poisonous gas. The resultant clinical picture is of hyperstimulation of both the nicotinic and muscarinic cholin...

Presentation and outcome of severe anticholinesterase insecticide poisoning.

AIMS To document the patterns of presentation and outcome of severe anticholinesterase insecticide poisoning in children requiring intensive care. METHODS Retrospective case note review of all 5541 children admitted to the paediatric intensive care unit (PICU) of a university hospital during the 10 years from January 1990 to May 2000. Fifty four children (1%) with anticholinesterase insectici...

Acute Anticholinesterase Pesticide Poisoning Caused a Long-Term Mortality Increase

Acute anticholinesterase pesticide (organophosphate and carbamate) poisoning (ACPP) often produces severe complications, and sometimes death. We investigated the long-term mortality of patients with ACPP because it is not sufficiently understood. In this retrospective nationwide population-based cohort study, 818 patients with ACPP and 16,360 healthy comparisons from 1999 to 2010 were selected ...

etiology, significance, diagnosis and treatment of bruxiam

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