Treating extremely low birthweight infants with prophylactic indomethacin

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Blood counts in extremely low birthweight infants.

White blood, neutrophil, and platelet counts were higher in 101 infants with appropriate weight for gestational age than in 42 infants who were small for gestational age. The recognised postnatal rise in counts was seen in the infants of appropriate weight, but in the infants who were small for gestational age the counts fell for the first three days.

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Stool microflora in extremely low birthweight infants.

AIM To serially characterise aerobic and anaerobic stool microflora in extremely low birthweight infants and to correlate colonisation patterns with clinical risk factors. METHODS Stool specimens from 29 infants of birthweight <1000 g were collected on days 10, 20, and 30 after birth. Quantitative aerobic and anaerobic cultures were performed. RESULTS By day 30, predominant species were Ent...

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Hypercalcaemia in extremely low birthweight infants.

We report 10 cases of hypercalcaemia associated with hypophosphataemia in the first two weeks of life in extremely low birthweight infants (birthweight less than 1000 g). At the time of diagnosis, the infants were fed mainly with expressed breast milk but they had also received intravenous nutrition. After treatment with additional phosphate plasma calcium concentrations returned to normal. The...

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Prophylactic indomethacin and intestinal perforation in extremely low birth weight infants.

OBJECTIVE Prophylactic indomethacin reduces severe intraventricular hemorrhage but may increase spontaneous intestinal perforation (SIP) in extremely low birth weight (ELBW) infants. Early feedings improve nutritional outcomes but may increase the risk of SIP. Despite their benefits, use of these therapies varies largely by physician preferences in part because of the concern for SIP. METHODS...

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Perinatal factors and adverse outcome in extremely low birthweight infants.

Perinatal factors associated with death or disability at 2 years were identified in an inborn cohort of 196 live births with a birth weight of 500-999 g. Antepartum haemorrhage, multiple pregnancy, breech presentation, perinatal asphyxia, hypothermia on admission, hyaline membrane disease, persistent pulmonary hypertension, severe respiratory failure, and intraventricular haemorrhage were assoc...

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ژورنال

عنوان ژورنال: BMJ

سال: 2002

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.324.7329.60