منابع مشابه
Acute traumatic coagulopathy and trauma-induced coagulopathy: an overview
Hemorrhage is the most important contributing factor of acute-phase mortality in trauma patients. Previously, traumatologists and investigators identified iatrogenic and resuscitation-associated causes of coagulopathic bleeding after traumatic injury, including hypothermia, metabolic acidosis, and dilutional coagulopathy that were recognized as primary drivers of bleeding after trauma. However,...
متن کاملTrauma-related Coagulopathy—Current Concepts
© T O U C H B R I E F I N G S 2 0 1 2 Tissue trauma induces alterations in the inflammatory and coagulation systems; in fact, the absence of such responses would almost certainly have resulted in our demise long ago. Along with our protective evolutionary devices, we have also increased our understanding of the coagulopathy induced by trauma over the last few decades—including its distinctive y...
متن کاملMechanisms of trauma-induced coagulopathy.
The identification and management of coagulopathy is a critical component of caring for the severely injured patient. Notions of the mechanisms of coagulopathy in trauma patients have been supplanted by new insights resulting from close examination of the biochemical and cellular changes associated with acute tissue injury and hemorrhagic shock. Acute intrinsic coagulopathy arising in severely ...
متن کاملCoagulopathy and blood component transfusion in trauma.
Trauma is a serious global health problem, accounting for approximately one in 10 deaths worldwide. Uncontrollable bleeding accounts for 39% of trauma-related deaths and is the leading cause of potentially preventable death in patients with major trauma. While bleeding from vascular injury can usually be repaired surgically, coagulopathy-related bleeding is often more difficult to manage and ma...
متن کاملAcute Traumatic Coagulopathy: an Endogenous Precursor of Trauma-induced Coagulopathy
Recent findings Trauma causes an acute disruption of the equilibrium between all components of haemostasis (coagulation, anticoagulation, fibrinolysis, platelets and endothelium). In patients with a combination of severe tissue damage and systemic hypoperfusion, this will progress rapidly to an endogenous coagulopathy that is independently associated with worse outcomes. New discoveries of the ...
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ژورنال
عنوان ژورنال: Medicina
سال: 2020
ISSN: 1648-9144
DOI: 10.3390/medicina56040205