Transmural recording of monophasic action potentials

Transmural recording of monophasic action potentials.

To investigate the possibility of transmural recording of repolarization through the ventricular wall, KCl monophasic action potential (MAP) electrodes positioned along plunge needles were developed and tested. The MAP electrode consists of a silver wire surrounded by agarose gel containing KCl, which slowly eluted into the adjacent tissue to depolarize it. In six dogs, a plunge needle containi...

Monophasic action potentials in man.

Localization of regional myocardial ischemia by recording of monophasic action potentials.

Identification of regional myocardial ischemia by TQ-ST segment mapping, while commonly used, is relatively imprecise and nonspecific. In 41 open-chest dogs we examined whether monophasic action potentials (MAPs) recorded from the myocardial surface by means of a new contact-electrode technique could be used to more precisely and specifically index regional myocardial ischemia. After ligation o...

LABORATORY INVESTIGATION MYOCARDIAL ISCHEMIA Localization of regional myocardial ischemia by recording of monophasic action potentials

Identification of regional myocardial ischemia by TQ-ST segment mapping, while comnmonly used, is relatively imprecise and nonspecific. In 41 open-chest dogs we examined whether monophasic action potentials (MAPs) recorded from the myocardial surface by means of a new contactelectrode technique could be used to more precisely and specifically index regional myocardial ischemia. After ligation o...

RECORDING OF MONOPHASIC ACTION POTENTIALS DuRING ISCHEMIA – REPERFuSION BY OPTICAL METHOD

The present paper deals with new possibility how to study ischemia and reperfusion in rabbit isolated heart perfused according to Langendorff. Electrogram was recorded by touch-less method and coronary flow measured throughout the experiment. Moreover, monophasic action potentials (MAPs) were obtained by optical probe using voltage-sensitive dye di-4-ANEPPS. Each experiment consisted from four ...