Transmissible Mink Encephalopathy: Studies on the Peripheral Lymphocyte
نویسندگان
چکیده
منابع مشابه
Transmissible mink encephalopathy.
Transmissible mink encephalopathy (TME) is a rare disease of ranch-raised mink caused by exposure to an as yet unidentified contaminated food ingredient in the ration. The clinical and pathological similarities between TME and scrapie, together with the indistinguishable physicochemical characteristics of their transmissible agents, suggest that sheep may be the source of infection. However, ex...
متن کاملTransmissible Mink Encephalopathy
Transmissible mink encephalopathy (TME) is a progressive and fatal neurodegenerative disease that affects ranched mink (Neovison (Mustela) vison). Most or all of the adult animals on a ranch may be affected, and once an animal becomes symptomatic, death is inevitable. This disease is still poorly understood. It is very rare, with only a few outbreaks reported in the U.S. and other countries. Ou...
متن کاملTransmissible mink encephalopathy: pathogenesis and nature of the aetiological agent.
A number of specific encephalopathies of mink are recognized, eg, Chasteks' paralysis-an haemorrhagic destruction of grey matter associated with hypothiaminosis (Innes and Saunders, 1962) and metachromatic leucodystrophy which has a sublethal autosomal recessive transmission (Brander and Palludan, 1965). The present paper concerns a disease characterized by spongy transformation of grey matter ...
متن کاملEvaluation of the Zoonotic Potential of Transmissible Mink Encephalopathy
Successful transmission of Transmissible Mink Encephalopathy (TME) to cattle supports the bovine hypothesis for the still controversial origin of TME outbreaks. Human and primate susceptibility to classical Bovine Spongiform Encephalopathy (c-BSE) and the transmissibility of L-type BSE to macaques indicate a low cattle-to-primate species barrier. We therefore evaluated the zoonotic potential of...
متن کاملScrapie and transmissible mink encephalopathy: search for infectious nucleic acid.
Brain preparations from animals with scrapie or transmissible mink encephalopathy were phenol extracted and examined for the presence of pathogenic nucleic acid. Animals inoculated with various extracts remained healthy, and analysis on 2.6 to 5% polyacrylamide gels failed to detect a difference in extractable RNA species between infected and normal mink brain.
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1973
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.7.3.352-355.1973