Transient ischemic attacks in a child with post-varicella arteriopathy and MTHFR homozigotic mutation C677T

Transient ischemic attacks in a child with post-varicella arteriopathy and MTHFR homozigotic mutation C677T.

Dr. Pedro Beleza – Serviço de Neurologia / Hospital São Marcos Largo Carlos Amarante, Apartado 2242 4701-965 Braga Portugal. E-mail: [email protected] Acute arteriopathies represent 79% of stroke in children. Chickenpox is the primary etiologic agent involved in 60% of cases and usually carries a good prognosis. We report on a patient with multiple transients ischemic attacks (TIA) who presen...

Factor V Leiden, MTHFR C677T and Prothrombin Gene Mutation G20210A in Iranian Patients with Venous Thrombosis

Background: Factor V Leiden, Prothrombin gene (G20210A) and MTHFR (C677T) polymorphism are the main biomarkers for evaluation of tendency for venous thromboembolism. We aimed to investigate the frequency of mutations in factor V Leiden, Prothrombin G20210A and MTHFR C677T and identify the genetic status for these mutations in patients with venous thrombosis. Methods: This study was carried out...

Transient Cerebral Arteriopathy in a Child Associated With Cytomegalovirus Infection

Vascular wall injuries account for up to 80% of childhood strokes, excluding emboli of cardiac origin. Transient cerebral arteriopathy is a recently described entity that is increasingly recognized as an important cause. The cerebral arterial wall is thought to be affected by an inflammatory process related to certain infections. The authors report a 2.5-year-old girl with sudden left hemiplegi...

Methyltetrahydrofolate Reductase C677T Mutation and 4G/5G Plasminogen Activator Inhibitor-1 Polymorphism in a Child with Deep Vein Thrombosis

Role of MTHFR C677T polymorphism in ischemic stroke.

BACKGROUND Homozygosity for MTHFR C677T polymorphism can lead to significantly high homocysteine levels and hyperhomocysteinemia is an important risk factor for thrombotic events. AIMS The aim was to determine role of MTHFR C677T polymorphism in North Indians with ischemic stroke. SETTINGS AND DESIGN In a prospective study, the subjects of stroke were recruited from the neurology clinic of ...