Transient Cloxacillin Induced Agranulocytosis with Eosinophilia and Elevated IgE Levels

Cloxacillin induced agranulocytosis: A rare adverse event of a commonly used antibiotic

Cloxacillin, a semisynthetic penicillin is a potent inhibitor of most penicillinase-producing Staphylococci. Use of high doses of Cloxacillin for 6 weeks is recommended for the treatment of infective endocarditis caused by methicillin-susceptible Staphylococcus aureus (MSSA). Here, we report a case of Cloxacillin-induced agranulocytosis in a patient treated for MSSA native tricuspid valve endoc...

Severe Agranulocytosis in Two Patients with Drug-induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms.

Prediction of elevated cord blood IgE levels by maternal IgE levels, and the neonate's gender and gestational age.

BACKGROUND Elevation of cord blood immunoglobulin E (IgE) is used to predict childhood atopy. In an effort to catch such problems at an earlier time, we sought to identify the impact of parental atopy as well as gestational age, the baby's gender, and the season of delivery on cord blood IgE levels. METHODS The allergic history of parents was collected during pregnancy. Blood samples from par...

Elevated serum levels of interleukin-5 in patients with the syndrome of episodic angioedema and eosinophilia.

The syndrome of episodic angioedema and eosinophilia is characterized by cyclic edema, marked peripheral blood eosinophilia, and eosinophil degranulation in the dermis. Using a sensitive immunoenzymetric method, we measured serum interleukin (IL)-5 levels in four patients with this syndrome. We also determined the percentage of activated T cells in the peripheral blood of a new patient before a...

Eosinophilia in the Allergic Mouse Down-Regulates Serum IgE Levels and Lung Oral Administration of Chitin