منابع مشابه
Transglutaminases in Crohn's disease.
Transglutaminases are a family of Ca-dependent enzymes involved in various biological events. Circulating transglutaminase (factor XIIIa) is decreased in blood of patients with inflammatory bowel diseases. There is evidence that factor XIIIa and tissue type transglutaminase, present in cell cytosol, bind to various proteins of the extracellular matrix. This study examined the value of serum tra...
متن کاملPinworm Infestation Mimicking Crohns' Disease
We here report a case of a young man who presented to his general practitioner with diarrhea. Inflammatory bowel disease was suspected and a colonoscopy showed aphthous lesions suggestive of Crohns' disease but biopsies revealed eggs of Enterobius vermicularis. When treated for this parasite, his symptoms were alleviated and a followup colonoscopy revealed a normal colon and distal ileum. Enter...
متن کاملChanges of Small Bowel Peristalsis in Patients with Crohns Disease
Purpose: MR enterography (MRE) is one of the mainstays in the evaluation of Crohns disease (CD). A wide variety of studies have attempted to improve the sensitivity and specificity of MRE, all focusing on the evaluation of static images [1]. MRE however allows not only the static display of morphology, but can be combined with ultrafast scanning techniques (cineMRE) for analysis of bowel motili...
متن کاملUlcerative colitis and Crohns disease: molecular genetics and clinical implications.
Derek Jewell Professor of Gastroenterology, Gastroenterology Unit, Radcliffe Infirmary, Oxford, OX2 6HE, UK. Tel: +44 (0) 1865 224829; Fax: +44 (0) 1865 790792; E-mail: [email protected] The genetics of inflammatory bowel disease (IBD) is an area of enormous topical interest. Crohn’s disease is one of the first polygenic diseases in which a susceptibility gene (NOD2 ) ...
متن کاملTransglutaminases in neurodegenerative disorders.
Type 2 transglutaminase (TG2) is a calcium-dependent acyltransferase which also undergoes a GTP-binding/GTPase cycle even though it lacks any obvious sequence similarity with canonical GTP-binding (G) proteins. As an enzyme which is responsible for the majority of transglutaminase (TG) activity in the brain, TG2 is likely to play a modulatory role in nervous system development and has regulator...
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ژورنال
عنوان ژورنال: Gut
سال: 1995
ISSN: 0017-5749
DOI: 10.1136/gut.37.5.690