Transglutaminase Transcription and Antigen Translocation in Experimental Renal Scarring
نویسندگان
چکیده
منابع مشابه
Myofibroblast phenotypes expression in experimental renal scarring.
BACKGROUND Myofibroblasts have been implicated in the pathogenesis of wound healing and tissue fibrosis. A role has also been put forward for these cells in the development of experimental and clinical renal scarring. SUBJECTS AND METHODS We examined the expression of myofibroblast phenotypes by immunohistochemistry, relying on an avidin-biotin-peroxidase method, during the course of renal sc...
متن کاملSpecific antagonism of PDGF prevents renal scarring in experimental glomerulonephritis.
Glomerular mesangial cell proliferation and/or mesangial matrix accumulation characterizes many progressive renal diseases. Rats with progressive mesangioproliferative glomerulonephritis were treated from day 3 to day 7 after disease induction with a high-affinity oligonucleotide aptamer antagonist against platelet-derived growth factor-B chain (PDGF-B). In comparison with nephritic rats that r...
متن کاملBacteriuria, reflux, and renal scarring
Much of the confusion in the discussion of these topics reflects differences of nomenclature not of fact, and a failure to relate the wide variation in severity both of reflux and of renal damage to their long-term implications. In this article, significant bacteriuria denotes the presence of actively multiplying organisms in the urinary tract and is indicated in girls by a pure growth of at le...
متن کاملRenal scarring and vesicoureteric reflux.
A review of 105 children with urinary tract infection showed an increasing prevalence of grades II-III vesicoureteric reflux with diminishing age. During infancy reflux was almost always severe, and affected boys as often as girls. Radiologically scarred kidneys were drained by refluxing ureters in 98% of cases. The prevalence of scars also rose significantly with increasinglyly severe reflux. ...
متن کاملBacteriuria, reflux, and renal scarring
Much of the confusion in the discussion of these topics reflects differences of nomenclature not of fact, and a failure to relate the wide variation in severity both of reflux and of renal damage to their long-term implications. In this article, significant bacteriuria denotes the presence of actively multiplying organisms in the urinary tract and is indicated in girls by a pure growth of at le...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 1999
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.v10102146