Transgenic Models of Insulin-Dependent Diabetes Mellitus

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Transgenic Models of Insulin- Dependent Diabetes Mellitus

Creswell, and O. Blair. 1992. Poly I:C induces development of diabetes mellitus in BB rat. Diabetes 41:515-520. Sternthal, E., A. A. Like, K. Sarantis, and L. E. Braverman. 1981. Lymphocytic thyroiditis and diabetes in the BB/W rat. A new model of autoimmune endocrinopathy. Diabetes 30:1058-1061. Thomas, V.A., B. A. Woda, E. S. Handler, D. L. Greiner, J. P. Mordes, and A. A. Rossini. 1991. Alte...

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Insulin-Dependent Diabetes Mellitus

From the School of Nursing (Drs Boehm, Schlenk, and Ronis and Ms Powers) and the Michigan Diabetes Research and Training Center, School of Medicine (Ms Funnell), University of Michigan, and the Department of Veteran’s Affairs (Dr Ronis), Ann Arbor, Michigan. Correspondence to Susan Boehm, PhD, Associate Professor and Dean, Student Affairs, The University of Michigan, School of Nursing, 400 Nort...

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Insulin effect on Leptin Concentration in Children with New Onset Insulin Dependent Diabetes Mellitus

Objective: Serum Leptin concentration reflects the body fat mass. There is controversial reports about the insulin effect on serum Leptin concentration. We wanted to examine the effect of insulin therapy on serum Leptin in children with new onset type I diabetes. Materials and Methods: This was a Cross-Sectional study in Children's Medical Center on 34 children who had new onset type I diabe...

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Polygenic models of non-insulin-dependent diabetes mellitus.

Non-insulin-dependent diabetes mellitus (NIDDM) is characterized by peripheral insulin resistance and insulin secretory dysfunction (1, 2). These abnormalities are either genetically defined or augmented by hyperglycemia itself, and may interact in a complex manner to cause and sustain hyperglycemia. Previous prospective studies have demonstrated that both insulin resistance/ hyperinsulinemia a...

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*Department of Microbiology and Immunology et al., 1995) and adhesion molecules (very late antigen School of Medicine 4) (Yang et al., 1993). University of North Carolina at Chapel Hill Studies of rodent models and preliminary studies in Chapel Hill, North Carolina 27599 man have shown that the completion of b cell destruc†Department of Microbiology and Immunology tion can beconsiderably delaye...

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ژورنال

عنوان ژورنال: ILAR Journal

سال: 1993

ISSN: 1084-2020

DOI: 10.1093/ilar.35.2.37