Transferring myoblasts in Duchenne dystrophy.

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Defective myoblasts identified in Duchenne muscular dystrophy.

A defect in the proliferative capacity of satellite cells, mononucleated precursors of mature muscle fibers, was found in clonal analyses of cells cultured from Duchenne muscular dystrophy (DMD) patients. The total yield of myoblasts per gram of muscle biopsy was decreased to 5% of normal. Of the DMD myoblast clones obtained, a large proportion contained a morphological class of flat distended ...

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Steroids in Duchenne dystrophy.

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ژورنال

عنوان ژورنال: BMJ

سال: 1992

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.305.6858.844