Transferable Multidrug-Resistance Plasmid Carrying a Novel Macrolide-Clindamycin Resistance Gene, erm (50), in Cutibacterium acnes
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چکیده
منابع مشابه
The multidrug resistance IncA/C transferable plasmid encodes a novel domain-swapped dimeric protein-disulfide isomerase.
The multidrug resistance-encoding IncA/C conjugative plasmids disseminate antibiotic resistance genes among clinically relevant enteric bacteria. A plasmid-encoded disulfide isomerase is associated with conjugation. Sequence analysis of several IncA/C plasmids and IncA/C-related integrative and conjugative elements (ICE) from commensal and pathogenic bacteria identified a conserved DsbC/DsbG ho...
متن کاملPrevalence of clindamycin-resistant Staphylococcus aureus induced by macrolide resistance
Introduction: Since the incidence of various infections caused by Staphylococcus aureus increases, the use of effective antibiotics such as clindamycin has been growing to treat the systemic and local infections caused by such organisms. Antibiotic-resistant species are emerging and spreading in today's communities due to misuse of antibiotics and incomplete treatment, turning into a serious ch...
متن کاملPlasmid-borne erm(T) from invasive, macrolide resistant Streptococcus pyogenes strains Running title: new GAS macrolide-resistance determinant. Key words: erythromycin and inducible clindamycin resistance, streptococcal plasmid, erm(T), methylase
Twenty-three group A streptococci (GAS) recovered from population-based invasive GAS surveillance in the United States were erythromycin-resistant, inducibly clindamycin-resistant and lacked known macrolide-resistance determinants. These 23 isolates, representing 4 different clones, contained a broad host-range plasmid carrying the erm(T) methylase gene which has not been previously detected in...
متن کاملAntimicrobial susceptibility and macrolide resistance inducibility of Streptococcus pneumoniae carrying erm(A), erm(B), or mef(A).
Erythromycin-resistant Streptococcus pneumoniae isolates from young carriers were tested for their antimicrobial susceptibility; additionally, inducibility of macrolide and clindamycin resistance was investigated in pneumococci carrying erm(A), erm(B), or mef(A). Of 125 strains tested, 101 (81%) were multidrug resistant. Different levels of induction were observed with erythromycin, miocamycin,...
متن کاملCharacterization of a novel small plasmid carrying the florfenicol resistance gene floR in Haemophilus parasuis.
Sir, The Gram-negative bacterium Haemophilus parasuis is the causative agent of Glässer’s disease, which is characterized by various combinations of meningoencephalitis, polyserositis, polyarthritis and bacterial pneumonia, resulting in major economic losses to the swine industry worldwide. Florfenicol is used exclusively in veterinary medicine and was approved for the treatment of porcine resp...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2020
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.01810-19