Transcriptomic biomarkers of human ageing in peripheral blood mononuclear cell total RNA

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Transcriptomic biomarkers of human ageing in peripheral blood mononuclear cell total RNA.

Age-related changes of gene expression contribute to the physiological alteration observed with human ageing. Herein, the abundance of a selection of 148 transcripts involved in immunosenescence and stress response was compared in total RNA of PBMC of healthy young to middle-age probands (35.0 +/- 6.5 year old) and healthy old probands (82.5 +/- 6.8 year old). This study provides a list of 16 d...

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ژورنال

عنوان ژورنال: Experimental Gerontology

سال: 2010

ISSN: 0531-5565

DOI: 10.1016/j.exger.2009.12.001