Transcriptome Analysis on Chinese Shrimp Fenneropenaeus chinensis during WSSV Acute Infection

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Transcriptome Analysis on Chinese Shrimp Fenneropenaeus chinensis during WSSV Acute Infection

Previous studies have discovered a lot of immune-related genes responding to white spot syndrome virus (WSSV) infection in crustacean. However, little information is available in relation to underlying mechanisms of host responses during the WSSV acute infection stage in naturally infected shrimp. In this study, we employed next-generation sequencing and bioinformatic techniques to observe the ...

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E2 Enzyme from Chinese White Shrimp Inhibits Replication of White Spot Syndrome Virus and Ubiquitinates its RING Domain Proteins Running title: Shrimp E2 ubiquitinates WSSV RING Domain proteins

Recent studies have shown that the ubiquitin proteasome pathway (UPP) is closely related to immune defense. We have identified a ubiquitin-conjugating enzyme E2 from the Chinese white shrimp Fenneropenaeus chinensis (FcUbc). Injection of recombinant FcUbc protein (rFcUbc) reduced the mortality of shrimp infected with White Spot Syndrome Virus (WSSV) and inhibited replication of WSSV. rFcUbc, bu...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2013

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0058627