Transcriptional Targeting in Cancer Gene Therapy

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چکیده

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Transcriptional Targeting in Cancer Gene Therapy

Cancer gene therapy has been one of the most exciting areas of therapeutic research in the past decade. In this review, we discuss strategies to restrict transcription of transgenes to tumour cells. A range of promoters which are tissue-specific, tumour-specific, or inducible by exogenous agents are presented. Transcriptional targeting should prevent normal tissue toxicities associated with oth...

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ژورنال

عنوان ژورنال: Journal of Biomedicine and Biotechnology

سال: 2003

ISSN: 1110-7243,1110-7251

DOI: 10.1155/s1110724303209074